Super Zhewitra is a combination medication that typically contains two active ingredients: Vardenafil and Dapoxetine. Vardenafil is used to treat erectile dysfunction (ED), while Dapoxetine is used to treat premature ejaculation (PE). As of my knowledge cutoff date in September 2021, let's discuss the safety of long-term use of Super Zhewitra:

Vardenafil (for ED): Vardenafil is a phosphodiesterase type 5 (PDE5) inhibitor, similar to Sildenafil and Tadalafil. Super Zhewitra works by increasing blood flow to the penis, helping men achieve and maintain an erection. PDE5 inhibitors are generally considered safe for short-term use and are well-tolerated by most individuals. However, there isn't enough long-term data available to definitively establish the safety of using PDE5 inhibitors like Vardenafil for extended periods, especially beyond a year or two.

Dapoxetine (for PE): Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) used to treat premature ejaculation. Its primary role is to help delay ejaculation and improve control over ejaculation. Like other SSRIs, Dapoxetine has been studied for longer-term use (up to a year) and is generally considered safe when used as prescribed. However, there may still be limited long-term data available regarding the safety of using Dapoxetine beyond this timeframe.