Vigora 50 mg contains the active ingredient sildenafil citrate, which belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. It works by increasing blood flow to the penis during sexual stimulation, thereby helping men to achieve and maintain an erection.

Here's how Vigora 50 mg influences blood flow:

Mechanism of Action: When a man is sexually aroused, the release of nitric oxide (NO) in the penis leads to the activation of an enzyme called guanylate cyclase. This enzyme increases levels of cyclic guanosine monophosphate (cGMP), which relaxes the smooth muscles of the blood vessels in the penis and allows them to dilate.

Inhibition of PDE5: Sildenafil citrate, the active ingredient in Vigora 50mg, works by inhibiting the action of phosphodiesterase type 5 (PDE5), an enzyme that breaks down cGMP. By inhibiting PDE5, sildenafil citrate helps to maintain higher levels of cGMP in the penis, prolonging its effects on blood vessel relaxation and dilation.

Increased Blood Flow: With higher levels of cGMP and relaxation of the smooth muscle cells in the blood vessels, there is increased blood flow into the penis. This enhanced blood flow results in the engorgement of the erectile tissues, leading to the achievement and maintenance of an erection sufficient for sexual activity.

Selective Action: It's important to note that sildenafil citrate has a selective action on the blood vessels in the penis and does not significantly affect blood flow in other parts of the body. This selective action minimizes the risk of systemic side effects while maximizing its effectiveness in treating erectile dysfunction.

Overall, Vigora 50 mg influences blood flow by enhancing the natural physiological processes involved in achieving an erection. It acts specifically on the blood vessels in the penis to promote vasodilation and increase blood flow, thereby helping men with erectile dysfunction to achieve and maintain satisfactory erections during sexual activity.